Fig. 1

Macrophage phenotypic changes after HCV antigen exposure. Monocytes from healthy donors (HC), healthy donors with HCV antigen stimulation (HS), treated patients (PT) and patients with liver injury (PTI) were treated with LPS/IFN-γ for polarization before analysis. (a) Gating strategy. (b) Mean fluorescence intensity (MFI) of TNF-α, TfR1, CD163 and CD23 expression on macrophages. One-way ANOVA was used to determine statistical significance (*p < 0.05, ***p < 0.001)