Fig. 1From: The multifunctional protein CI of potyviruses plays interlinked and distinct roles in viral genome replication and intercellular movementThe localization of the four conserved domains of the CI protein of TuMV and the substitution residues of CI mutants. Conserved domains are determined according to NCBI conserved domain database (CDD). The Potyvirid-P3 superfamily (aa 2–57) is underlined in purple. The DEAD- like helicases superfamily (73–230) that involved in ATP-dependent RNA or DNA unwinding are underlined in green, the helicase superfamily (246–368) in red, and the potyviridae polyprotein superfamily (386–644) in blue. Amino acids substituted with alanine in this article are colored in red, and the name of mutants containing double-substitutions are indicated above or under the mutated residues. Seven motifs (I, Ia, II, III, IV, V and VI) highly conserved for the superfamily 2 of RNA helicases are indicated in orange boxes according to [15]Back to article page