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Fig. 2 | Virology Journal

Fig. 2

From: The M, F and HN genes of genotype VIId Newcastle disease virus are associated with the severe pathological changes in the spleen of chickens

Fig. 2

Gene map illustrating gene replacement strategy in Herts/33 backbone and pathogenicity of the recombinant viruses. Three unique restriction sites in the JS5/05 genome and the PacI in the Herts/33 genome were used to replace viral genes. Intracerebral pathogenicity index (ICPI) and mean death time (MDT) were measured to evaluate the pathogenicity of the chimeric viruses. For designation of the chimeric viruses, Herts/33 backbone is shown in short as Hert and the donator virus JS5/05 is shown as superscript

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