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Table 1 Summary of production of L2-recombinant Ad5 virions. Shown are the designation of each L2-recombinant adenovirus, the nature of the L2 insert, the site of hexon into which it was inserted, the mode of insertion and the pfu of virus obtained upon a standard preparation

From: Capsid display of a conserved human papillomavirus L2 peptide in the adenovirus 5 hexon protein: a candidate prophylactic hpv vaccine approach

Construct Insert (a.a.) Hexon site (a.a.) Mode Particles/ml
5 ins HPV16 271–272 HVR5 Insertion 2.2 × 1012
L2 12–41
5 sub HPV16 271–281 HVR5 Substitution 2.37 × 1012
L2 12–41
1 sub HPV16 138–167 HVR1 Substitution 1.80 × 1012
L2 12–41
1 ins HPV16 128–129 HVR1 Insertion 1.76 × 1012
L2 12–41