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Table 1 The EC50 and EC90 values for copper phthalocyanine sulfate (CuPcS) preventing HIV-1 pseudovirus infection of TZM-BL cells were determined with a nonlinear regression model and was comparable across pseudovirus subtypes

From: In vitro antiretroviral activity and in vivo toxicity of the potential topical microbicide copper phthalocyanine sulfate

Efficacy for pre-treatment of HIV with CuPcS

 

EC50 μg/ml

EC90 μg/ml

SVPB6

50.32

151.6

SVPB11

26.33

79.35

SVPB12

6.467

19.49

SVPB13

21.04

63.41

SVPB16

12.59

37.94

SVPB14

16.67

50.24

SVPB15

43.93

132.4

SVPB19

33.24

100.2

SVPB8

49.92

150.4