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Fig. 8 | Virology Journal

Fig. 8

From: Construction of a recombinant duck enteritis virus (DEV) expressing hemagglutinin of H5N1 avian influenza virus based on an infectious clone of DEV vaccine strain and evaluation of its efficacy in ducks and chickens

Fig. 8

Safety of DEV-H5(UL55) for chickens. A total of 50 1-week-old SPF chickens were randomly divided into five groups of A-AI(1C), B-AI(1C), C-AI(1C), D-AI(1C), and E-AI(1C). In groups A-AI(1C), B-AI(1C), and C-AI(1C), chickens were vaccinated intramuscularly with DEV-H5(UL55) at a dose of 1 × 107 TCID50 (Line 107), 1 × 106 TCID50 (Line: 106), and 1 × 105 TCID50 (Line: 105), respectively. Chickens in group D-AI(1C) were inoculated subcutaneously with a dose of 0.3 ml of inactivated AIV H5N1 Re-6 vaccine (QYH) (Line: Re-6). Chickens in the control group E-AI(1C) were inoculated with 0.2 ml PBS (Line: Control). All birds were observed for clinical signs over the 14 days after inoculation. The survival rates of these five groups over the 14 days are shown here

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Virology Journal

ISSN: 1743-422X