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Table 4 Analysis of the overall data from the collaborative study. The results of the collaborative study by method were compared to the virus content (titer) of the national standard (National Institute of Food & Drug Safety Evaluation, code no. 08/027) (titer unit: log10PFU/dose)

From: Standardization of the methods and reference materials used to assess virus content in varicella vaccines

Method

Result

Nc

Meand ± SDe

95 % CIf

PSMa

81

4.50 ± 0.14

0.17, 0.27

AOMb

65

4.27 ± 0.26

  1. a PSM, Plaque staining method
  2. b AOM, Agar overlay method
  3. c N, Number of tests
  4. d Mean, Geometric mean titer
  5. e SD, Standard deviation
  6. f CI, Confidence interval
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Virology Journal

ISSN: 1743-422X