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Fig. 2 | Virology Journal

Fig. 2

From: In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses

Fig. 2

Compound ca603 (black) inhibits HRV14 replication only when added at an early stage and behaves similar to pleconaril (grey). Compounds were added prior to, at the time of, or after viral infection at indicated time points and viral RNA was quantified 8 h pi. Intracellular viral RNA load was expressed as equivalents of 50 % tissue infective dose/mL (log (TCID50/mL) eq.) (mean ± STD from two independent assays). Insert: Intracellular viral HRV14 RNA increased from baseline input (0 h) till 8 h post-infection (one full virus replication cycle)

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Virology Journal

ISSN: 1743-422X