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Fig. 4 | Virology Journal

Fig. 4

From: Patient-derived hepatitis C virus inhibits CD4+ but not CD8+ T lymphocyte proliferation in primary T cells

Fig. 4

CD4+ and CD8+ T cell proliferation rates after exposure to HCV. Lymphoid cells from the same healthy donor were stained with CFSE, PHA-stimulated and infected as described in Materials and Methods to measure proliferation of CD4+ and CD8+ T cell subsets. a Graphical representation of proliferation of T cell subsets after exposure to either NHP or HCV inocula. Proliferation represented by the mean percentage CFSE low ± SEM was measured at 4, 7 and 10 d.p.i. b The rates of T cell subset proliferation in cultures exposed to individual HCV inocula or NHP. Proliferation is represented by the mean percentage CFSE-low ± SEM measured at 3 different time points during the 10-d.p.i. culture

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