TY - JOUR AU - MacParland, Sonya A. AU - Chen, Annie Y. AU - Corkum, Christopher P. AU - Pham, Tram N.Q. AU - Michalak, Tomasz I. PY - 2015 DA - 2015/06/19 TI - Patient-derived hepatitis C virus inhibits CD4+ but not CD8+ T lymphocyte proliferation in primary T cells JO - Virology Journal SP - 93 VL - 12 IS - 1 AB - Hepatitis C virus (HCV) can replicate in cells of the immune system and productively propagate in primary T lymphocytes in vitro. We aimed to determine whether exposure to authentic, patient-derived HCV can modify the proliferation capacity, susceptibility to apoptosis and phenotype of T cells. SN - 1743-422X UR - https://doi.org/10.1186/s12985-015-0322-4 DO - 10.1186/s12985-015-0322-4 ID - MacParland2015 ER -