Table 3 Pooled unadjusted risk estimates of ACLF after stratification or matching
Mutation site | Matching factor | OR | _LCI | _UCI | P |
|---|---|---|---|---|---|
T1753V | unmatched | 1.919 | 1.414 | 2.606 | 0.000 |
age and sex matched | 1.481 | 0.982 | 2.234 | 0.061 | |
age, sex, genotype and HBV DNA matched | ND | ND | ND | ND | |
A1762T | unmatched | 2.685 | 2.264 | 3.185 | 0.000 |
age and sex matched | 2.307 | 1.555 | 3.422 | 0.000 | |
age, sex, genotype and HBV DNA matched | 1.326 | 0.585 | 3.007 | 0.499 | |
G1764A | unmatched | 2.901 | 2.041 | 4.122 | 0.000 |
age and sex matched | 2.023 | 1.013 | 4.041 | 0.046 | |
age, sex, genotype and HBV DNA matched | 1.310 | 0.555 | 3.094 | 0.538 | |
A1762T/G1764A | unmatched | 2.376 | 1.548 | 3.648 | 0.000 |
age and sex matched | 2.602 | 1.270 | 5.333 | 0.009 | |
age, sex, genotype and HBV DNA matched | ND | ND | ND | ND | |
G1896A | unmatched | 2.181 | 1.800 | 2.642 | 0.000 |
age and sex matched | 2.014 | 1.505 | 2.695 | 0.000 | |
age, sex, genotype and HBV DNA matched | 1.479 | 1.017 | 2.152 | 0.041 | |
G1899A | unmatched | 3.525 | 2.882 | 4.312 | 0.000 |
age and sex matched | 3.171 | 2.464 | 4.081 | 0.000 | |
age, sex, genotype and HBV DNA matched | ND | ND | ND | ND | |
C1766T | unmatched | 1.849 | 1.403 | 2.437 | 0.000 |
age and sex matched | 1.719 | 1.226 | 2.411 | 0.002 | |
age, sex, genotype and HBV DNA matched | ND | ND | ND | ND | |
T1768A | unmatched | 2.199 | 1.563 | 3.094 | 0.000 |
age and sex matched | 2.203 | 1.425 | 3.405 | 0.000 | |
age, sex, genotype and HBV DNA matched | ND | ND | ND | ND | |
A1846T | unmatched | 3.163 | 2.157 | 4.639 | 0.000 |
age and sex matched | 2.854 | 2.127 | 3.831 | 0.000 | |
age, sex, genotype and HBV DNA matched | ND | ND | ND | ND |