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Table 4 Performance characteristics of the KHB/STAT-PAK®/Unigold™ tiebreaker algorithm with dilution as a supplementary test compared to gold standard (N = 2895)

From: Dilution testing using rapid diagnostic tests in a HIV diagnostic algorithm: a novel alternative for confirmation testing in resource limited settings

Dilution

Sensitivity (95 % CI)

Specificity (95 % CI)

PPV (95 % CI)

NPV (95 % CI)

1/10

100 % (95.8-100)

99.9 % (99.6-100)

98.4 % (96.0-99.6)

100 % (98.5-100)

1/40

100 % (98.5-100)

100 % (99.8-100)

99.6 % (97.8-100)

100 % (98.5-100)

1/160

99.6 % (97.8-100)

100 % (98.5-100)

100 % (98.5-100)

100 % (99.8- 100)

1/640

98.8 % (96.5-99.8)

100 % (98.5-100)

100 % (98.5-100)

99.9 % (99.7-100)

1/2560

97.2 % (94.3-98.9)

100 % (98.5-100)

100 % (98.5-100)

99.7 % (99.5-99.9)

1/10,240

89.5 % (85.0-93.0)

100 % (98.5-100)

100 % (98.3-100)

99.0 % (98.6-99.4)