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Table 1 Database search for NP-41I/V and/or NP-210D/E mutations in virus isolates from nature

From: Residues 41V and/or 210D in the NP protein enhance polymerase activities and potential replication of novel influenza (H7N9) viruses at low temperature

Mutations

Human

Swine

Avian

Canine

Equine

Other residues

NP-41V

6

14

197

42

98

I(13,763), A(2), G(3), K(1), M(1), Q(8), T(6), Y(1)

(n = 357)

NP-210D

9

4

143

0

0

E(13960), G(2), N(9), P(3), Q(2), R(3), X(7)

(n = 156)

NP-41V + 210D

6

0

19

0

0

(n = 25)

  1. The data shown are the number of sequences with identical amino acid composition (NP-41 and NP-210) of 14,142 influenza isolates in the NCBI database. The total number of each residue is shown in parentheses.