Figure 5

HPV11 transcription map obtained in transiently transfected U2OS cells. The HPV11 ORFs, LCR, promoters (P90, P264, P674-714, P1092, and P1372) and polyadenylation CSs (Cs 4384 and Cs 7485) are shown at the top of the figure. All of the HPV11 transcripts from transiently transfected U2OS cells (indicated with letters from A-Q, shown at left) are presented, showing the exons (solid boxes), introns (lines) and splicing donor and acceptor sites (nt numbers in HPV11 genome). The inferred 5′ ends of the RT-PCR products (N-Q) are indicated with dashed boxes. The coding potential is described to the right of each transcript, and references are provided when similar transcripts were found by others, namely, Chiang et al. [23], Chow et al. [20], and Renaud et al. [26].