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Table 1 Antiviral activity (IC 50 ) against HCV, cytotoxicity (CC 50 ) and selectivity index (SI) of crude venoms of five Egyptian scorpion species tested in this study

From: Virocidal activity of Egyptian scorpion venoms against hepatitis C virus

Species

IC 50 (μg/ml) a

CC 50 (μg/ml) a

SI

Leiurus quinquestriatus

>100

>100

na

Androctonus amoreuxi

>100

>100

na

Androctonus australis

88.3 ± 5.8

>300

>3.4

Androctonus bicolor

>100

>100

na

Scorpio maurus palmatus

6.3 ± 1.6

>100

>15.8

  1. a: Data represent means ± SEM of the data obtained from two independent experiments using the J6/JFH1-P47 strain of HCV.
  2. na: Not applicable.