Figure 1

Dose-dependent anti-HCV activity of S. maurus palmatus venom. A fixed amount of HCV was mixed with serial dilutions of S. maurus palmatus venom and inoculated to Huh7.5 cells at a multiplicity of infection of 0.5 pfu/cell. After virus adsorption, the cells were cultured with the same concentrations of the venom for 46 hr. The culture supernatants were harvested and titrated for virus infectivity. Percent inhibitions of HCV infectivity by the venom at the concentrations of 0.1 to 100 μg/ml are shown. Data represent means ± SEM of the data obtained from two independent experiments.