Figure 3

Histopathological findings in experimentally PRV-infected beagle dogs. A: Stellate ganglion, salient gliosis and neuronophagia (arrow), and nuclear debris from necrotic cells are frequently observed (HE); B: stellate ganglion, showing mild hemorrhage (HE); C: stellate ganglion, acidophilic intranuclear inclusion bodies (arrow) (HE); D: cardiac muscle, extensive myocardial hemorrhage and necrosis in the myocardium, swelling and vacuolization of the muscle fibers, loss of striation, and granular fibers are visible (HE); E: cardiac muscle, less-severe changes with the accumulation of eosinophilic fiber-like exudates in the myocardial interstitium (HE); F: lung, pulmonary hemorrhage and congestion (HE); G: ileum, lymphoid depletion in the lymphatic nodules (starry sky aspect) (HE); H: cecum, mild hemorrhage in the lymphoid nodules (HE); I: thymus, mild hemorrhage (HE); J: thymus, showing lymphoid-depleted areas (HE); K: mesenteric lymph nodes, showing lymphoid depletion (HE); L: adrenal gland, hemorrhage in the zona fasciculata, ZG, zona glomerulosa; ZF, zona fasciculata (HE).