Table 1 The efficiency of formononetin and pirodavir against EV71 in vitro
From: Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE2 expression
Cell Compound | Vero | SK-N-SH | ||||||
|---|---|---|---|---|---|---|---|---|
TC0 (μmol/L) | TC50 (μmol/L) | IC50(μmol/L) | SI | TC0 (μmol/L) | TC50 (μmol/L) | IC50 (μmol/L) | SI | |
Formononetin | 41.42 ± 0 | 149.38 ± 12.15 | 3.45 ± 0.55 | 43.30 | 55.92 ± 0 | 198.80 ± 6.02 | 3.98 ± 0.80 | 49.95 |
Pirodavir | 7.52 ± 0 | 22.33 ± 1.71 | 0.38 ± 0.08 | 58.76 | 10.83 ± 0 | 30.30 ± 4.03 | 0.23 ± 0.04 | 131.74 |