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Figure 3 | Virology Journal

Figure 3

From: Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE2 expression

Figure 3

Formononetin but not pirodavir reduces the phosphorylation of ERK (A), p38 (B), and JNK (C) induced by EV71 infection. SK-N-SH cells (9 × 105 cells/well) were plated into 6-well culture plates. The cells were then pretreated with formononetin (14.91 μmol/L) and pirodavir (1.08 μmol/L), respectively. After 24 h, the cells were mock-infected or infected with 4.8 × 105 pfu/well of EV71 (SHZH98) for 15 min (A), 10 min (B), and 30 min (C), respectively. The cells were harvested and ERK (A) p-ERK (A), p38 (B), p-p38 (B), JNK (C), and p-JNK (C) were detected by western blot.

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