Phylogenetic trees of clinical viral isolates based on the analysis of 400 nt from the 5′-UTR hypervariable region of the RV genome. The tree branches of each 5′-genotype in the RV-A and RV-C trees are labeled with a different color; genotype numbering starts at the gap in the circle and increases counterclockwise. The names of the sequences starting with “gi” correspond to reference strains downloaded from GenBank and are depicted with grey triangles. The blue squares represent viruses detected in outpatient children, and their names start with the two initial letters of the city where the sample was collected (CO, Córdoba; MI, Minatitlán; PR, Poza Rica; TB, Tierra Blanca; VE, Veracruz). The red circles indicate viruses detected in hospitalized children, and the names of the hospitals from which the sample was collected are coded as follows: DGO, Hospital General de Durango; HCGDL, Hospital Civil de Guadalajara; HGMDF, Hospital General de México, D.F.; HPCDF, Hospital Pediátrico de Coyoacán, D.F.; GDL, Hospital de Pediatría, IMSS; SLP, Hospital Central de San Luis Potosí. The gray circles in the phylogenetic tree for RV-A species represent the terminal clades of the tree that were identical to the terminal clades of the tree constructed with full genomic sequences . The reference strains (gi) that are not contained in the gray circles are marked with a dot at the end of the name, and represent sequences that do not match with the terminal clades of the reference, full genomic sequences tree. The database of reference strains contained only those viruses with complete genomic sequences. The numbers after the colors in the vertical bar represent the 5′-genotype of the virus, as described in the -Genetic diversity of RV- section of results.