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Table 2 Serum HBV-infection markers in the tree shrews of group B

From: Chronic hepatitis B virus infection and occurrence of hepatocellular carcinoma in tree shrews (Tupaia belangeri chinensis)

Animal Infection markers in serum * Weeks after inoculation
6 12 24 36 48 ~150 ** ~250 **
108-4 HBV DNA /# - - ± ± - -
  HBsAg / / / / - - -
  HBsAb / / / / + ± -
  HBeAg / / / / - - -
  HBeAb / / / / - - -
  HBcAb / / / / - - -
117 HBV DNA 1.10 × 103 - ± - - 1.92 × 103 -
  HBsAg ± ± - - - - -
  HBsAb + + - ± - + +
  HBeAg - - - - - - -
  HBeAb - - - - - - -
  HBcAb - - - - - + -
122-2 HBV DNA - ± - - - - -
  HBsAg ± ± - - - - -
  HBsAb + + ± ± - + +
  HBeAg - - - - - - -
  HBeAb - - - - - - +
  HBcAb - - - - - - +
131-3 HBV DNA ± ± - - ± - -
  HBsAg - - - - - - -
  HBsAb + + ± ± - - -
  HBeAg - - - - - - -
  HBeAb - + ± ± - - -
  HBcAb - + - ± - - +
133-2 HBV DNA 1.24 × 103 3.01 × 103 ± 3.5 × 103 - - -
  HBsAg - - - - - - -
  HBsAb + + ± - - - -
  HBeAg - - - - - - -
  HBeAb + + ± - - - -
  HBcAb - + - - - - -
133-3 HBV DNA ± 1.04 × 103 ± 1.12 × 104 1.46 × 104 - -
  HBsAg - - - - - - -
  HBsAb - ± ± - - - -
  HBeAg - - - - - - -
  HBeAb - - + + + - -
  HBcAb - + + + + - -
136-2 HBV DNA - - - - - - -
  HBsAg - - - - - - -
  HBsAb - ± + + ± + ±
  HBeAg - - - - - - -
  HBeAb - + - - + - -
  HBcAb - + - + + - -
137-2 HBV DNA ± - - ± ± - -
  HBsAg - - -   - - -
  HBsAb - - + - + + +
  HBeAg - - - + - - -
  HBeAb - - + - - - -
  HBcAb - - - - - - -
140-3 HBV DNA 1.31 × 103 ± - / - - -
  HBsAg - - - / - - -
  HBsAb - + - / - ± -
  HBeAg - - - / - - -
  HBeAb - - - / - - +
  HBcAb + + - / - - -
  1. *HBV DNA in serum was detected by FQ-PCR, the results were expressed as values of IU/ml (positive), “-” (values < 0.5 × 102 IU/ml) or “±” (values between 0.5 × 102-1.0 × 103 IU/ml). Serum HBsAg, HBsAb, HBeAg, HBeAb and HBcAb were detected by ELISA, the results were expressed as “+” (positive), “-” (negative) or “±” (between positive and negative).
  2. **“~150” means around 150 weeks. “~250” means around 250 weeks, the last time of detection.
  3. #Not tested at this time point.
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Virology Journal

ISSN: 1743-422X