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Figure 4 | Virology Journal

Figure 4

From: Chronic hepatitis B virus infection and occurrence of hepatocellular carcinoma in tree shrews (Tupaia belangeri chinensis)

Figure 4

Histological images of the liver tumors. A. Neoplastic cells. The neoplastic cells showed marked cellular pleomorphism. Multinucleated cells (arrow) and abnormal mitoses (insert) were evident. Tumor tissue of 98–2, HE staining, 200× and 400× (insert) respectively. B. Morphological patterns. Three morphological patterns were found in tumors. The solid pattern was the tumor cells arranged in sheets with little intervening stroma and lack of sinusoids (two upper panels). The trabecular pattern was the tumor cells arranged in short and irregular cords (lower left panel). The pseudoglandular pattern was the tumor cells arranged as glandular structures (lower right panel). Tumor tissues of 98–2 (upper panels) and 121–1 (lower panels), HE staining, 200×.

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