Skip to main content
Figure 2 | Virology Journal

Figure 2

From: A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture

Figure 2

Inhibition of DENV-2 NS2b-NS3Pro by MB21 and in silico analysis of the interaction between the two. (A) Inhibition of protease activity of cloned DENV-2 NS2b-NS3Pro as a function of MB21 concentration. (B) Computer generated 2D ligand interaction picture depicting the interaction between MB21 and DENV-2 NS2b-NS3Pro. Hydrophobic residues are shown in green. (C) Interaction of MB21 at the allosteric pocket in the vicinity of the catalytic triad.

Back to article page

Virology Journal

ISSN: 1743-422X