Table 4 Novel HPV16 E6 variants, regional distribution, collection year and lesion in cervical epithelium
Patient | HPV 16 E6 Novel variant | Accession number GenBank | Nucleotide change | Amino acid change (not previously reported) | Women residence (City/State region) | Diagnosis/Sampling year | Follow up Diagnosis/Year |
|---|---|---|---|---|---|---|---|
1 | E-A176/G424/G350 | KJ465994 | G424 | - | Atoyac/Coast | Cervical carcinoma 2003 | - |
2 | E-C183/G350 | KJ465995 | C183 | I27T | Chilpancingo/Center | Non-IL 2002 | LSIL 2006 |
3 | E-C183/G350 | KJ465995 | C183 | I27T | Chilpancingo/Center | Non-IL 2006 | LSIL 2009 |
4 | E-C183/G350 | KJ465995 | C183 | I27T | Chilpancingo/Center | Non-IL 2002 | - |
5 | E-C188/G310/G350 | KJ465996 | G310 | - | Chilpancingo/Center | Non-IL 2004 | Non-IL 2005 |
6 | E-C188/G310/G350 | KJ465996 | G310 | - | Chilpancingo/Center | LSIL 2009 | LSIL 2012 |
7 | E-G189/T256/G350 | KJ465998 | G189 and T256 | - | Chilpancingo/Center | LSIL 2008 | LSIL 2009 |
8 | E-C306/G350 | KJ465997 | C306 | K68T | Acapulco Coast | Non-IL 2003 | - |
9 | E-G535/G350 | KJ465999 | G535 | - | Tepecoacuilco/North | LSIL 2006 | - |
10 | AA-a/C188 | KJ465992 | C188 | - | Iguala/North | Non-IL 1997 | - |
11 | AA-c/G185 | KJ465993 | G185 | - | Juchitan/North | Cervical carcinoma 1998 | - |