Cohort 1 (N = 5) | Cohort 2 (N = 12) | Cohort 3 (N = 12) | All (N = 29) | |||||
---|---|---|---|---|---|---|---|---|
Subject-reported symptoms | n | % | n | % | n | % | n | % |
Headache | 2 | 40.0 | 4 | 33.3 | 7 | 58.3 | 13 | 44.8 |
Nasal stuffiness/congestion | 2 | 40.0 | 5 | 41.7 | 5 | 41.7 | 12 | 41.4 |
Sore throat | 1 | 20.0 | 5 | 41.7 | 5 | 41.7 | 11 | 37.9 |
Sneezing | 1 | 20.0 | 4 | 33.3 | 6 | 50.0 | 11 | 37.9 |
Cough | 1 | 20.0 | 4 | 33.3 | 5 | 41.7 | 10 | 34.5 |
Hot/feverish/chills/rigor | 1 | 20.0 | 5 | 41.7 | 4 | 33.3 | 10 | 34.5 |
Runny nose | 1 | 20.0 | 3 | 25.0 | 5 | 41.7 | 9 | 31.0 |
Musculoskeletal ache | 2 | 40.0 | 3 | 25.0 | 3 | 25.0 | 8 | 27.6 |
Fatigue | 2 | 40.0 | 3 | 25.0 | 3 | 25.0 | 8 | 27.6 |
Breathing difficulty | 1 | 20.0 | 2 | 16.7 | 3 | 25.0 | 6 | 20.7 |
Diarrhoea | 0 | 0.0 | 4 | 33.3 | 2 | 16.7 | 6 | 20.7 |
Earache | 0 | 0.0 | 3 | 25.0 | 2 | 16.7 | 5 | 17.2 |
Facial or eye pain | 0 | 0.0 | 2 | 16.7 | 3 | 25.0 | 5 | 17.2 |
Hoarseness | 1 | 20.0 | 1 | 8.3 | 1 | 8.3 | 3 | 10.3 |
Nausea/vomiting | 0 | 0.0 | 2 | 16.7 | 1 | 8.3 | 3 | 10.3 |
Wheezy chest | 0 | 0.0 | 0 | 0.0 | 1 | 8.3 | 1 | 3.4 |
Physician-reported signs | n | % | n | % | n | % | n | % |
Pharyngitis | 1 | 20.0 | 7 | 58.3 | 10 | 83.3 | 18 | 62.1 |
Nasal discharge | 0 | 0.0 | 8 | 66.7 | 8 | 66.7 | 16 | 55.2 |
Otitis | 0 | 0.0 | 0 | 0.0 | 6 | 50.0 | 6 | 20.7 |
Sinus tenderness | 0 | 0.0 | 3 | 25.0 | 2 | 16.7 | 5 | 17.2 |
New wheezes/crackles/rhonchi | 0 | 0.0 | 0 | 0.0 | 2 | 16.7 | 2 | 6.9 |
Percussion | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
Pyrexia | n | % | n | % | n | % | n | % |
Temperature >37.7°C | 2 | 40.0 | 3 | 25.0 | 2 | 16.7 | 5 | 17.2 |