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Table 1 Demographic variables and BDV infection prevalence in study participants

From: Health care professionals at risk of infection with Borna disease virus – evidence from a large hospital in China (Chongqing)

  I, MDD outpatients II, Hospital personnel III, Healthy, controls P -value  
     Group I vs. II Group I vs. III Group II vs. III All three groups
Sample size 534 615 380     
Age (year) a, b 35.99 ± 12.23 39.28 ± 11.61 35.58 ± 10.86 0.000 0.885 0.000 0.000e
<25 116 38 57     
25-39 217 284 193     
40-54 147 226 105     
55-70 54 56 25     
>70 0 11 0     
Sex (M/F) c 187/347 182/433 160/220 0.049 0.030 0.000  
HDRS score a,d 20.58 ± 7.00 2.2 ± 0.8 1.2 ± 1.0 0.000 0.000 0.143  
CIC+ (%) c 97 (18.2%) 134 (21.8%) 42 (11.1%) 0.001 0.024 0.000  
p24 RNA+ (%) c 27 (5.1%), 50 (8.1%), 8 (2.1%), 0.038 0.022 0.000  
CIC+ and p24 RNA + c 21 (3.9%), 48 (7.8%) 5 (1.3%) 0.006 0.019 0.000  
CIC+ and/or p24 RNA + c 103 (19.3%), 136 (22.1%), 45 (11.8%), 0.239 0.003 0.000  
CIC- and p24 RNA+ 6 2 3     
CIC level        0.197f
Negative and borderline 437 454 332     
Weakly/1+ positive 82 134 42     
2+ positive 14 23 6     
3+ and 4+ positive 1 4 0     
Antibody+/CIC+ 5/50 3/50 4/40     
Antibody+/CIC+ 0/50 1/50 1/40     
  1. Abbreviations: MDD major depressive disorder, M male, F female, HDRS Hamilton Depression Rating Scale, CIC circulating immune complexes, p24 BDV phosphoprotein 24, RNA ribonucleic acid. aValues expressed as means ± SDs.,bMann-Whitney test,cChi-square test,dOne-way ANOVA,eKruskal-Wallis test,fSpearman correlation.