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Table 2 HPV results of ICC and CIN2/3 specimens tested by heat extraction and the RealTime assay

From: Identification of human papillomaviruses from formalin-fixed, paraffin-embedded pre-cancer and invasive cervical cancer specimens in Zambia: a cross-sectional study

  ICC CIN 2/3
  n Prevalence (95% CI) n Prevalence (95% CI)
Total tested 114 -- 75 --
Total with valid resultsa 100 -- 69 --
  Positive for any HPVb 93 -- 65 --
  HPV-16 positive 48 51.6% (41.6–61.5) 36 55.4% (43.3–66.8)
  HPV-18 positive 23 24.7% (17.1–34.4) 5 7.7% (3.3–16.8)
  Other HR HPV positive 38 40.9% (31.4–51.0) 43 66.2% (54.0–76.5)
HPV-16 and/or HPV-18 positive 65 69.9% (59.9–78.3) 38 58.5% (46.3–69.6)
  1. aInvalid results mean the β-globin internal control was not reactive or had a Ct value of >35.
  2. bIncluding specimens with multiple HPV types identified. The number of specimens that were positive for HPV was used as the denominator for prevalence estimates.