Table 1 Summary of identified bait-prey interactions and previous reports of host protein association with influenza A virus

PAICS

Phosphoribosylaminoimidazole carboxylase

Yes

3

R3, R9, R15

Karlas et al. [40], Kumar and Nanduri [47], Kroeker et al. [48]

MSANTD3

Myb/SANT-like DNA-binding domain containing 3

No

3

R10, R13, R27

N/A

FLJ30306

PREDICTED: Homo sapiens uncharacterized LOC101059922, mRNA

Yes

2

R23, R33

N/A

PA28B

Proteasome activator subunit 2

Yes

2

R6, R19

N/A

KCTD9

Potassium channel tetramerisation domain containing 9

No

2

R34, R36

N/A

ACOT13

Acyl-CoA thioesterase 13

Yes

1

R11

N/A

TRA2B

Transformer 2 beta homolog (Drosophila)

Yes

1

R12

Zhu et al. [56]

SLC30A9

Solute carrier family 30 (zinc transporter), member 9

No

1

R28

Kumar and Nanduri [47], Sui et al. [44]

ATP1B1

ATPase, Na+/K+ transporting, beta 1 polypeptide

No

1

R7

Mi et al. [51], Liu et al. [50]

CKAP5

Cytoskeleton associated protein 5

No

1

R29

N/A

BAT1/UAP56

RNA-dependent ATPase

N/A

N/A

Momose et al. [30]

HSP40

Heat shock protein 40

N/A

N/A

Sharma et al. [26]

NPI-1/ SRP1/KPNA1

Karyopherin α1

N/A

N/A

O’Neill and Palese [27], Shapira et al. [28]

KPNA3

Karyopherin α3

N/A

N/A

Shapira et al. [28]

KPNA6

Karyopherin α6

N/A

N/A

Shapira et al. [28]

C16orf45

-

N/A

N/A

Shapira et al. [28]

GMCL1

Germ cell-less, spermatogenesis associated 1

N/A

N/A

Shapira et al. [28]

MAGED1

Melanoma antigen family D.1

N/A

N/A

Shapira et al. [28]

MLH1

MutL homolog 1

N/A

N/A

Shapira et al. [28]

USHBP1

Usher syndrome 1C binding protein 1

N/A

N/A

Shapira et al. [28]

ZBTB25

Zinc finger and BTB domain containing 25

N/A

N/A

Shapira et al. [28]

CLU

Clusterin

N/A

N/A

Tripathi et al. [29]

ALY/REF

RNA export adaptor protein

N/A

N/A

Balasubramaniam et al. [31]

ACTN4

Alpha-actinin 4

N/A

N/A

Sharma et al. [34]