Figure 1
From: E5564 inhibits immunosuppressive cytokine IL-10 induction promoted by HIV-1 Tat protein
E5564 inhibits LPS-induced production of IL-10 by primary human monocytes. Primary human monocytes were treated or not by anti-TLR4 blocking antibodies (1 μg/ml), or with placebo (10 nM) or with E5564 (10 nM) before stimulation by increasing concentration of LPS (1, 2, 5 ng/ml). The data represent means concentrations of IL-10 in culture supernatants ± SD of three independent experiments.