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Table 1 Pathogenicity of the SW/3/06 virus in different avian species

From: The pathogenicity of swan derived H5N1 virus in birds and mammals and its gene analysis

Species (inoculation route)

Mortalitya

MDT (days)

Dose (EID50)b

Antibody titer on indicated day post-infectionc

14

21

28

White Leghorns (i.v.)

10/10

3.3

104.3

ND

ND

ND

White Leghorns (i.n.)

6/6

3.4

104.3

ND

ND

ND

White Leghorns (i.m.)

6/6

3.6

104.3

ND

ND

ND

Kholmogory geese (i.n.)

0/6

>28.0

104.3

4.7 ± 0.6

6.0 ± 0.0

7.0 ± 1.0

Kholmogory geese (i.m.)

0/6

>28.0

104.3

4.3 ± 0.6

5.3 ± 0.6

6.0 ± 0.0

Silver Bantam ducks (i.n.)

6/6

4.2

104.3

ND

ND

ND

Silver Bantam ducks (i.m.)

6/6

5.2

104.3

ND

ND

ND

Czech turkeys (i.n.)

6/6

1.6

104.3

ND

ND

ND

Czech turkeys (i.m.)

6/6

1.8

104.3

ND

ND

ND

  1. aNumber of birds that died/number of birds inoculated.
  2. bDetermined by back titer determination of the inoculum; EID50, 50% egg infectious dose.
  3. cPresented as Log2 HI titer ± standard deviation. Antibody titers were determined by an HI assay of two-fold diluted serum.
  4. ND, not determined.