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Table 1 The eIF4G cleavage activity obtained with different variants of CVB3 2A pro

From: Protease 2A induces stress granule formation during coxsackievirus B3 and enterovirus 71 infections

2A mutant eIF4G cleavage activity*
Wild-type + + +
D39E + + +
L40F + + +
S67F + +
Y89L + + +
Y90L + +
V120M + + +
G122E +/-
D136N + + +
  1. *The 2A protease activity was determined to be undetectable (-), detectable in some assays (+/-), or positive (+ to + + +).
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Virology Journal

ISSN: 1743-422X