Figure 1
From: Protease 2A induces stress granule formation during coxsackievirus B3 and enterovirus 71 infections
CVB3 infection induces SG formation. (A) HeLaEGFP-TIA1 cells were mock infected, exposed to 0.5 mM NaArs for 30 min, or infected with CVB3 (MOI =10) for 3 h. The cells were then fixed and stained for HuR. (B) HeLaEGFP-TIA1 cells were infected with CVB3 as discribed in (A). The cells were then fixed and stained for G3BP1. (C) HeLa cells, co-transfected with pEGFP-eIF4G and pmCherry-HuR, were infected with CVB3 as discribed in (A). The cells were then fixed and imaged. Nuclei were identified by Hoechst 33342 staining. Cells were examined using a fluorescence microscopy (×400).