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Table 2 Effects of fraction A/isolated ursolic acid in combination with acyclovir on HSV-1 F infected Vero cells

From: Anti-herpes virus activities of bioactive fraction and isolated pure constituent of Mallotus peltatus: an ethnomedicine from Andaman Islands

Fraction/Compound

Mean EC50 ± SDa

FICfraction/compound + FICacyclovirb

Inhibitory effect

Fraction A

7.8 ± 1.6

-

-

Ursolic acid (isolated)

5.5 ± 0.54

-

-

Acyclovir alone

2.1 ± 0.1

-

 

Acyclovir + Fraction A

2.7 ± 0.15

0.84

No interaction

Acyclovir + isolated ursolate

2.51 ± 0.12

0.78

No interaction

  1. a Results are the mean of three independent experiments of MTT assay.
  2. b FICfraction/compound + FICacyclovir are FICs of fraction/compound and acyclovir, respectively.
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Virology Journal

ISSN: 1743-422X