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Table 2 Protective efficacy of the live attenuated H5N1 influenza vaccine in chickens

From: The new temperature-sensitive mutation PA-F35S for developing recombinant avian live attenuated H5N1 influenza vaccine

Vaccine groups# Challengingvirus Positive/total No. (HI antibody, log2)before challenge Death rate Shedding/total (log10EID50/ml ± SE)
trachea cloacal
ts-C4/W1 C4 0/6 6/6$ ND (dead&) ND (dead)
  D6 0/6 6/6 ND (dead) ND (dead)
C4/W1-PA(F35S) C4 6/6* (2.3) 0/6 0/6 0/6
  D6 5/6 (2.6) 0/6 0/6 0/6
PBS C4 0/6 6/6 ND (dead) ND (dead)
  D6 0/6 6/6 ND (dead) ND (dead)