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Table 2 Comparison of the clinical data from patients with different enteroviruses

From: Distribution of enteroviruses in hospitalized children with hand, foot and mouth disease and relationship between pathogens and nervous system complications

 

EV71

CA16

OE

p value

Total

Total (n)

89

68

20

 

177

Gender (Male, n)

52(58.4%)

38(55.9%)

14(70%)

0.528

104(58.8%)

Age*(Years)

2.382 ± 2.102

2.588 ± 1.860

1.875 ± 1.146

0.347

 

Region (from countryside, n)

57(64%)

41(60.3%)

13(65%)

0.868

111(62.3%)

Time from onset to hospitalization (d) â‘¡

3.258 ± 1.176

4 ± 1.258

3.6 ± 1.353

0.001

 

Duration of hospitalization (d)

14.337 ± 17.796

9.338 ± 3.366

8.1 ± 3.354

0.182

 

WBC > 12 × 10 9 (n)

51(57.3%)

32(47.1%)

11(55%)

0.437

94(530.1%)

CRP > 8 mg/dl (n)

4(4.5%)

3(4.4%)

1(5%)

0.994

8(4.5%)

Duration of initial fever(d)

6.034 ± 3.131

5.706 ± 1.684

5.45 ± 1.468

0.547

 

Highest fever temperature (°C) ③

39.144 ± 0.563

38.919 ± 0.494

38.92 ± 0.618

0.025

 

Hand or foot rash (n)

81(91%)

67(98.5%)

20(100%)

0.057

168(94.9%)

Oral rash (n)

58(65.2%)

50(73.5%)

15(75%)

0.451

123(69.5%)

Buttock rash (n)

39(43.8%)

28(41.2%)

6(30%)

0.525

73(41.2%)

No rash (n)

3(2.2%)

0

0

0.221

3(1.7%)

Accompanied nervous system damage

65(73%)

19(27.9%)

8(40%)

0.000

92(52%)

Patients with dysfunction upon discharge (n)

11(12.4%)

1(1.5%)

1(5%)

0.030

13(7.3%)

Death (n)

5(7.3%)

0

0

0.030

5(2.8%)

  1. *Patients aged 0-12 months were counted as being 0.5 years of age; patients aged 1-2 years were counted as being 1.5 years of age; patients aged 2-3 years were counted as being 2.5 years of age, etc. ¤Among the 5 fatal cases, 2 patients died of neurogenic pulmonary edema, 2 died of shock, and 1 was diagnosed as being brain-dead. ② Statistically significant difference between groups A and B but no difference in comparison to the other 2 groups. ③There is statistically significant difference between group A and groups B and C but no difference in comparison to the other 2 groups