Table 1 Performance of HVR1 variants in detecting anti-HCV antibodies
Coating Ag | No positive/no tested | ||||
|---|---|---|---|---|---|
| Â | Genotype 3 | Genotype 1 | Genotype 4 | Genotype 6 | Total |
Variant 1 | 68/85 (80%) | 18/25 (72%) | 4/4 | 1/1 | 91/115 (79.1%) |
Variant 2 | 61/85 (71.7%) | 15/25 (60%) | 1/4 | 0/1 | 77/115 (67%) |
Variant 3 | 74/85 (87%) | 24/25 (96%) | 2/4 | 1/1 | 101/115 (87.8%) |
Variant 4 | 79/85 (92.9%) | 22/25 (88%) | 4/4 | 1/1 | 106/115 (92.2%) |
Pool | 63/85 (74.1%) | 17/25 68%) | 2/4 | 1/1 | 83/115 (72.2%) |
Tetramer | 38/85 (44.7%) | 10/25 (40%) | 0/4 | 1/1 | 49/115 (42.6%) |