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Table 2 Detection of FMDV RNA in blood and respiratory tract samples (nasal and pharyngeal swabs) from challenged pigs

From: Inclusion of a specific T cell epitope increases the protection conferred against foot-and-mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site

   

Day post-challenge

   

0

3

7

10

Group

Inoculum

Pig

B a

N b

P c

B

N

P

B

N

P

B

N

P

1

B peptide

B1

-

nad

na

+

na

na

-

na

na

-

na

na

  

B2

-

na

na

+

na

na

+

na

na

-

na

na

  

B3

-

- e

-

-

+ f

+

-

-

-

-

-

-

  

B4

-

-

-

-

-

+

-

+

+

-

-

-

  

B5

-

-

-

+

-

+

+

+

+

-

-

-

  

B6

-

-

-

+

+

+

-

+

+

-

-

-

2

TB peptide

TB1

-

na

na

+

na

na

-

na

na

-

na

na

  

TB2

-

na

na

-

na

na

-

na

na

-

na

na

  

TB3

-

-

-

+

-

+

-

-

-

-

-

-

  

TB4

-

-

-

-

-

+

-

-

-

-

-

-

  

TB5

-

-

-

-

-

-

-

-

-

-

-

-

  

TB6

-

-

-

-

-

-

-

-

+

-

-

-

3

PBS

C1

-

-

-

+

+

+

+

+

+

-

+

-

  

C2

-

-

-

+

+

+

-

+

-

-

+

-

  

C3

-

-

-

+

+

+

-

+

-

-

+

-

  

C4

-

-

-

+

+

+

+

+

+

-

-

-

  1. a Blood
  2. b Nasal swabs
  3. c Pharyngeal swabs
  4. d sample not available
  5. e RNA not detected
  6. f RNA detected