S gene mutations of HBV in children with HBV-associated glomerulonephritis

Table 3 HBV S gene mutations and the inferred amino acid substitutions in children with HBV-GN

Case No.	amino acid loci in S region	Codon change	Amino acid substitutions
1	94	TTG→ TCG	Leu→ Ser
2	161	TTC→ TGC	Phe→ Cys
3	143	TCG→ ATG	Ser→ Met
	161	TTC→ TGC	Phe→ Cys
	200	TAT→ TTT	Tyr→ Cys
	122	AAA→ AAG	Lys
	125	ACA→ ACG	Thr
	136	TCA→ TCC	Ser
	155	TCT → TCC	Ser
4	122	AAA→ AAG	Lys
5	164	GAG→ GGG	Glu→ Gly
6	200	TAT→ TTT	Tyr→ Cys
7	125	ACA→ ACG	Thr
8	143	TCG→ ATG	Ser→ Met
9	204	AGT→ AGA	Ser→ Arg
	125	ACA→ ACG	Thr
10	96	GTT→ GGT	Val→ Gly
	200	TAT→ TTT	Tyr→ Cys
11	161	TTC→ TGC	Phe→ Cys
12	155	TCT → TCC	Ser
13	122	AAA→ AAG	Lys
	136	TCA→ TCC	Ser
14	45	ACA→ ACT	Thr
15	127	CCT→ ACT	Pro→ Thr
16	143	TCG→ ATG	Ser→ Met
	161	TTC→ TGC	Phe→ Cys
	122	AAA→ AAG	Lys
	125	ACA→ ACG	Thr
	136	TCA→ TCC	Ser
	155	TCT → TCC	Ser
17	129	CAA→ CAC	Gln→ His
	119	GGA→ GGC	Gly
18	129	CAA→ CAC	Gln→ His
	119	GGA→ GGC	Gly
	125	ACA→ ACG	Thr
19	129	CAA→ CAC	Gln→ His
	125	ACA→ ACG	Thr
20	175	CAT→CGT	His→ Arg
21	198	ATG→ ACG	Met→ Thr
others	No mutation

ISSN: 1743-422X