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Figure 7 | Virology Journal

Figure 7

From: Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

Figure 7

Atomic model of HPV16 L1 in the context of the T = 7 VLP. (A) A single subunit of L1 in the standard orientation. Residues 261-297 are in red and form part of the H16.V5, H16.E70, H263.A2 and H16.J4 epitopes. Residues 339-365 are in pink and form part of the H263.A2, H16.V5 and H16.E70 epitopes. Residues 174-185 are in dark green and form the H16.H5 epitope. Residues 111-130 are in blue and form the H16.I23 epitope. (B) A pentameric L1 capsomere with the same coloring scheme as in (A) and with the subunit in the foreground in approximately the same orientation as in (A). (C) A view of the HPV16 VLP surface with the capsomere in yellow in the same orientation as in (B) and heparin oligosaccharides as they bind to L1 capsomeres shown in red. The atomic model was generated as described in the Methods.

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