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Figure 3 | Virology Journal

Figure 3

From: Design of different strategies of multivalent DNA-based vaccination against rabies and canine distemper in mice and dogs

Figure 3

CDV-neutralizing antibody titers in mice inoculated with pCMV3ISS-CDVH or Tetradog®. Groups of mice were administered intramuscularly either 50 μg of pCMV3ISS-CDVH; or 200 μl of Tetradog® and compared to sham vaccinated mice (50 μg of pCMV3ISS) and non-vaccinated mice (PBS). All the mice were blood-sampled two and four week’s post-vaccination. Titers were expressed as the highest dilution of sera that inhibited the cytopathic effect of CDV-Onderstepoort strain. Results correspond to the mean antibody titers (the highest dilution of sera that inhibited the cytopathic effect of CDV-Onderstepoort strain) of 5 mice per group. Stars indicate statistical significances of differences between groups of mice administered either pCMV3ISS-CDVH, or Tetradog®.

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