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Figure 5 | Virology Journal

Figure 5

From: Over-expression of mitochondrial antiviral signaling protein inhibits coxsackievirus B3 infection by enhancing type-I interferons production

Figure 5

Inhibition of CVB3 and up-regulation of IFNs by MAVS introduction after CVB3 infection. After exposure to CVB3 for 1 h, pcDNA3.1 and pcDNA3.1-FLAG-MAVS were introduced into HeLa cells. In 0 h ~ 36 h, cells were harvested and total RNA was extracted. (A) CVB3 RNA, (B) IFN-β mRNA and (C) IFN-α mRNA were detected through RT-qPCR. * p < 0.05,** p < 0.01.

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