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Figure 3 | Virology Journal

Figure 3

From: Surveillance in eastern India (2007-2009) revealed reassortment event involving ns and PB1-F2 gene segments among co-circulating influenza a subtypes

Figure 3

Result of ConSurf server. ConSurf server identified the conserved regions among the deduced amino acid sequences of NS1 and NS2 protein of eastern India strains, with respect to concurrent vaccine strains [A/Brisbane/59/2007(H1N1) and A/Brisbane/10/2007(H3N2)]. The degree of conservation was subdivided into nine grades, with grade 1 being the least and grade 9 being most conserved. Figure 3A, 3B and 3C, 3D represents the NS1 and NS2 protein of A/H1N1 and A/H3N2, respectively. Although amino acid residues especially at positions 4, 21, 22, 44, 53, 59, 60, 103 and 106 were conserved among the vaccine strains as well as all other eastern India strains, ConSurf server predicted the lowest score for these amino acid residues suggesting them as highly variable residues of grade 1.

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Virology Journal

ISSN: 1743-422X