Figure 5

Amino acid sequence variability of the VESV-like virus VP1 proteins.. A) Multiple sequence alignment of the VP1 P2 regions of the VESV-like viruses Asterisks indicate positions where differences in amino acid sequences between strains v810 and 780032I are observed. Structural elements such as β−strands and α−helices found in the structure of SMSV4 VP1 are depicted above the alignment as hollow box arrows and coils, respectively. B) Ribbon and surface representation of the SMSV4 VP1 protein and its virus capsid assembly inferred using the Chimera program. Color coding of the alignment, ribbon structure and virus capsid were generated using the ConSurf software and is based on variability scale from 0 to 100%, with the most variable residues colored dark purple.