Figure 2
From: Isolation of avian influenza H5N1 virus from vaccinated commercial layer flock in Egypt
Predicted location of amino acid substitutions found in the isolated virus on the tertiary structure of HA H5 (A) and N1 NA (B) monomers. Shown are the substitutions in D43N, S120N, I151T and S320G in the HA and A46D, N200D, L224M, S339V and S450G in the NA proteins. Substitutions have been imposed upon the tertiary structure of A/chicken/Egypt/06207-NLQP/2006(H5N1) (index virus of clade 2.2.1 introduced into Egypt in early 2006). Protein modeling was generated by JIGSAW[28] and edited by RasTop version 2.7.1 and further edited by Inkscape.