Performance and diagnostic usefulness of commercially available enzyme linked immunosorbent assay and rapid kits for detection of HIV, HBV and HCV in India

Table 3 Performance characteristic of HIV, HBsAg and HCV rapid kits used for comparative evaluation

Test Parameter	Kit Company	Lot	Kit Performance
			Sensitivity		Specificity		PPV		NPV		Efficiency
			(%)	%Mean (95%CI)	(%)	%Mean(95%CI)	(%)	%Mean (95%CI)	(%)	%Mean (95%CI)	(%)	%Mean (95%CI)
HIV	J. Mitra & Co. Pvt. Ltd.	1	100	98.3 (95.7-101.0)	100	100 (100–100)	100	100 (100–100)	100	98.9 (97.2-100.6)	100	99.3 (98.3-100.4)
		2	100		100		100		100		100
		3	95.0		100		100		96.8		98.0
	SPAN Diag. Ltd.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100
	Standard. Diag. Inc.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100
HBsAg	J. Mitra & Co. Pvt. Ltd.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100
	SPAN Diag. Ltd.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100
	Standard. Diag. Inc.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100
HCV	J. Mitra & Co. Pvt. Ltd.	1	95.5	95.5 (91.2-99.7)	100	100 (100–100)	100	100 (100–100)	96.6	96.6 (93.5-99.8)	98.0	98.0 (96.1-99.8)
		2	90.9		100		100		93.3		96.0
		3	100		100		100		100		100
	SPAN Diag. Ltd.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100
	Standard. Diag. Inc.	1	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)	100	100 (100–100)
		2	100		100		100		100		100
		3	100		100		100		100		100

CI- Confidence Interval, PPV-Positive Predictive Value, NPV-Negative Predictive Value.

ISSN: 1743-422X