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Figure 3 | Virology Journal

Figure 3

From: Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model

Figure 3

Time-dependent viral replication after hydrodynamic transfection in vivo. Mice were injected hydrodynamically with 10μg pHBV4.1 (Wt) or pHBV rt A181T/sW172 (Mut) respectively, and were sacrificed at different time points. A: HBV DNA replication intermediates of mice livers were detected by Southern blotting. B: Quantitative analysis of HBV DNA replication intermediates. The levels of HBV DNA replication intermediates in Wt group on day 1 were defined as 1.

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