Skip to main content

Table 2 Genotype frequency of toll-like receptor (TLR) polymorphisms in the study population

From: Toll-like receptor 3 gene polymorphisms and severity of pandemic A/H1N1/2009 influenza in otherwise healthy children

Polymorphism genotypes

A/H1N1/2009-positive children admitted because of ILI(n=51)

A/H1N1/2009-negative children admitted because of ILI(n=221)

Healthy controls (n=164)

TLR2 rs5743708

 GG

49 (96.1)

218 (98.6)

161 (98.2)

 GA

2 (3.9)

3 (1.4)

3 (1.8)

p-value, HWE

0.89

0.92

0.91

TLR3 rs5743313

 CC

26 (51.0)

124 (56.1)

92 (56.1)

 TT

4 (7.8)

12 (5.4)

9 (5.5)

 CT

21 (41.2)

85 (38.5)

63 (38.4)

p-value, HWE

0.93

0.60

0.67

TLR3 rs5743315

 CC

46 (90.2)

208 (94.1)

149 (90.9)

 AC

5 (9.8)

13 (5.9)

15 (9.1)

p-value, HWE

0.71

0.65

0.54

TLR4 rs4986790

 AA

46 (90.2)

202 (91.4)

148 (90.2)

 AG

5 (9.8)

19 (8.6)

16 (9.8)

p-value, HWE

0.71

0.50

0.51

TLR4 rs4986791

 CC

46 (90.2)

203 (91.9)

148 (90.2)

 TT

0 (0.0)

1 (0.5)

0 (0.0)

 CT

5 (9.8)

17 (7.6)

16 (9.8)

p-value, HWE

0.71

0.33

0.51

  1. HWE: Hardy-Weinberg equilibrium; ILI: influenza-like illness; TLR: toll-like receptor. Percentages in parentheses. No significant between-group difference.