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Table 1 Demographic and clinical characteristics of the study population

From: Toll-like receptor 3 gene polymorphisms and severity of pandemic A/H1N1/2009 influenza in otherwise healthy children

Characteristics

A/H1N1/2009-positive children admitted because of ILI(n=51)

A/H1N1/2009-negative children admitted because of ILI(n=221)

Healthy controls (n=164)

Males, No. (%)

27 (52.9)

109 (49.3)

85 (51.8)

Caucasians, No. (%)

51 (100.0)

221 (100.0)

164 (100.0)

Mean age ± SD, yrs

3.16 ± 3.46

3.43 ± 3.79

3.39 ± 3.88

Age groups, No. (%)

 <2 years

5 (9.8)

28 (12.7)

15 (9.1)

 2-5 years

44 (86.3)

182 (82.4)

140 (85.4)

 >5 years

2 (3.9)

11 (5.0)

9 (5.5)

Median number of siblings (range)

1 (0–4)

1 (0–3)

1 (0–4)

Exposure to passive smoking, No. (%)

15 (29.4)

69 (31.2)

43 (26.2)

Day care or school attendance, No. (%)

49 (96.1)

210 (95.0)

158 (96.3)

Previous pneumococcal vaccination, No. (%)

46 (90.2)

199 (90.0)

143 (87.2)

Previous pandemic A/H1N1/2009 influenza vaccination, No. (%)

0 (0.0)

3 (1.4)

2 (1.2)

Diagnosis, No. (%)

 Common cold

15 (29.4)

78 (35.2)

NA

 Pharyngitis

14 (27.5)

75 (33.9)

NA

 Acute otitis media

4 (7.8)

21 (9.5)

NA

 Pneumonia

18 (35.4)

47 (21.2)

NA

 Minor surgical problem

NA

NA

164 (100.0)

Hospitalised at enrolment, No. (%)

18 (35.4)

47 (21.2)

NA

  1. ILI: influenza-like illness; NA: not applicable; SD: standard deviation. Percentages in parentheses. No significant between-group difference.