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Table 2 Summary of correlation analysis between the dimensional factors (DF) in COA and sixteen dinucleotides frequencies in H1N1 pdm IAV ORFs

From: Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development

  

UU

UC

UA

UG

CU

CC

CA

CG

Mean ± SDa

 

0.893 ± 0.0054

0.814 ± 0.0050

0.736 ± 0.0009

1.215 ± 0.0009

0.797 ± 0.0056

0.672 ± 0.0033

1.326 ± 0.0042

0.319 ± 0.0020

DF 1b

r

0.43277

0.30726

0.50328

0.49116

0.16033

0.40283

0.44451

0.47789

P

<0.0001

<0.0001

<0.0001

<0.0001

0.0048

<0.0001

<0.0001

<0.0001

  

AU

AC

AA

AG

GU

GC

GA

GG

Mean ± SDa

 

1.281 ± 0.0046

0.926 ± 0.0039

1.804 ± 0.0071

1.327 ± 0.0037

0.682 ± 0.0076

0.703 ± 0.0009

1.472 ± 0.0012

1.040 ± 0.0018

DF 1b

r

0.44790

0.36540

0.61328

0.40489

0.08304

0.49579

0.48484

0.45555

P

<0.0001

<0.0001

<0.0001

<0.0001

0.11880

<0.0001

<0.0001

<0.0001

  1. a Mean values of 310 H1N1 pdm IAV strains’ relative dinucleotide ratios ± standard deviation. b Correlation analysis between the first dimensional factor in COA and the sixteen dinucleotides frequencies in H1N1 pdm IAV ORF’s is shown.
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Virology Journal

ISSN: 1743-422X