Table 1 Comparison of immunogenicity of formalin-inactivated RG and wild-type (wt) viruses
Antigen | Log2 (titer of neutralizing antibody) against (mean (SD)): | ||||||
|---|---|---|---|---|---|---|---|
EV71-B2 | EV71-B4 | EV71-B5 | EV71-C1 | EV71-C2 | EV71-C4 | EV71-C5 | |
B5-wt | 7(0.89) | 7.8(0.98) | 8(0.89) | 5.1(0.75) | 5.7(0.75) | 4.2(0.75) | 4.7(0.82) |
B5-RG1 | 7(1.26) | 7.3(1.03) | 7.8(0.75) | 4.8(0.75) | 5(0.63) | 4.3(0.82) | 4.83(0.75) |
B5-RG2 | 7(0.89) | 7.16(1.17) | 8 (0.63) | 4.6(0.82) | 5.2 (0.4) | 4.2(0.98) | 4.5(0.55) |
PBS | < 3 | < 3 | < 3 | < 3 | < 3 | < 3 | < 3 |